Cancer Genomics Testing

Cancer Genomics is the study of gene mutations that may be driving a cancer’s behavior. These tests are critical in finding your risk factor to certain cancers as well as helping establish preventative care plans.

Common Hereditary Cancers and Cancer Syndromes:

  • P Breast, Ovarian, Endometrial, Uterine Cancer (BRCA1, BRCA2)
  • P Colon, Renal, Pancreatic, Gastric, Liver Cancer(APC, BMPR1A, EPCAM)
  • P Lynch Syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM)
  • P Prostate Cancer (BRCA1, BRAC2, EPCAM, MLH1, MSH2, MSH6, NBN, PMS2, STK11)
  • P Pancreatic Cancer (APC,ATM, BMPR1A, BRCA1, BRCA2, CDKN2A, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, RINT1, STK11,SMAD4, TP53,VHL,XRCC2)
  • P Melanoma Cancer (BRCA1, BRCA2, CDKN2A, EPCAM, MLH2, MSH2, PTEN, TP53)

Who qualifies for hereditary cancer testing?

  • An individual who has or had, more than one cancer.
  • An individual with a personal history of cancer with limited availability of family history and single-gene testing has not found a mutation, or the result is uncertain.
  • An individual who has multiple close family members with a cancer diagnosis under the age of 50.
  • An individual with family members who have taken a cancer genetic test and mutations were identified.
  • An individual being a member of a racial or ethnic group that is known to have an increased risk of having a certain inherited cancer susceptibility syndrome.
  • An individual with a personal or family history of cancer and single-gene testing has not found a mutation, or unclear results.
  •  An individual with rare or unusual cancer presentations.

Why is This Significant?

Earlier the detection the better

Individuals may begin to get cancer screens earlier and more often.

Individuals may begin to monitor themselves closely for signs or symptoms of a particular type of cancer.

Individuals may initiate healthy lifestyle changes and preventive measures.

Individuals may look into preventive medications or surgery if recommended by a physician.